Information: After Abnormal Hepatitis C Screening Results

If your HCV antibody test is positive

Get an HCV RNA test: This is the crucial next step to determine if you have a current, active infection.

• • A positive RNA test means you have an active infection, and your doctor will need to discuss treatment options.
  • A negative RNA test means the virus is no longer in your body, likely because you cleared the infection naturally or were previously cured. You will still test positive for antibodies, so the RNA test is necessary to know your current status.

Talk to your doctor: Inform your doctor about your test results and discuss the next steps. They will use this information to determine the best course of action.

If you have an active infection (positive antibody and positive RNA test)

• Get a genotype test: This test identifies the specific strain of the hepatitis C virus you have, which is important for selecting the most effective treatment plan.
• Have a fibrosis assessment: A doctor will evaluate the extent of any liver damage, which can be done through blood tests, an imaging test like magnetic resonance elastography (MRE), or a liver biopsy.
• Consider additional screening: Your doctor may recommend screening for other infections, such as HIV and Hepatitis B, because they are often spread through similar routes.
• Consult a specialist: For optimal outcomes, especially with inexperienced providers, referral to a specialist with expertise in hepatitis C treatment is often recommended.